Dual stimuli-responsive smart beads that allow "on-off" manipulation of cancer cells.
نویسندگان
چکیده
Temperature- and electric field-responsive polymer-conjugated polystyrene beads, termed smart beads, are designed to isolate cancer cells. In smart beads, the reversible "on-off" antigen-antibody reaction and dielectrophoresis force on an electrode are accomplished to realize "on-off" remote manipulation of smart beads and cancer cells. Both the zeta-potential and the hydrodynamic diameter of the smart beads are sensitive to temperature, allowing "on-off" reversible capture and release of cancer cells. Cancer cell-captured smart beads are then localized on electrodes by applying an electrical signal.
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ورودعنوان ژورنال:
- Biomaterials science
دوره 4 6 شماره
صفحات -
تاریخ انتشار 2016